AN EMERGING COMPLIMENTARY MEDICINE-YOLK OIL MADE FROM HEATING METHOD | Author : TSUNG-MING HU, TSUO-HUNG LAN, EL-WUI LOH | Abstract | Full Text | Abstract :Yolk oil is common in Asia. According to the Flora Sinensis, yolk oil is a multipurpose medicine, with specific dermatological and fever indications. Nowadays, it is generally used as a complimentary medicine for heart diseases. Yolk oil can be made from heating or chemical extraction method. It is generally believed that yolk oil made from heating (YOheat) method is more effective as a medicine than that from extraction (YOext). The technical details of the heating method remain an issue of argument, including the degree of char and the threat of carcinogens formed during the heating process. Most yolk oil related studies used YOext as research material. Nevertheless, animal studies have showed that YOheat reduced triglycerides and total cholesterol in rodent liver. It is expected an easy-to-make complimentary medicine like YOheat may become even more common and thus evidence based studies should be conducted to verify its pharmacological effects and safety. |
| THE CORRELATION OF TRADITIONAL CHINESE MEDICINE DEFICIENCY SYNDROMES, CANCER RELATED FATIGUE, AND QUALITY OF LIFE IN BREAST CANCER PATIENTS | Author : TSAI-JU CHIEN, YOU-LUNG SONG, CHE-PIN LIN, CHUNG-HUA HSU | Abstract | Full Text | Abstract : Background: To evaluate the correlation between the different traditional chinese medicine (TCM) deficiency syndromes, cancer related fatigue (CRF), and quality of life (QoL) in breast cancer patients. Patients and methods: Ninety-five breast cancer patients were categorized into different qi (? qì ), blood (? xuè) , yin (? yin), and yang (? yáng) TCM deficiency syndrome groups (DSGs). We used the ICD-10 for diagnosing CRF. The QoL was assessed by the WHO-BREF and Short Form Health Survey (SF12) questionnaires. The major outcome was to compare the QoL scores between the different TCM DSGs. The second outcome was the intergroup analysis between the CRF and different TCM DSGs in breast cancer patients. Results: The patients with qi deficiency (?? qì xu) had a higher correlation with CRF (p=0.001) and poorer QoL both in the WHO-BREF and SF12 survey (p0.001), whereas the patients with yin deficiency (?? yin xu) had poorer QoL in the psychological (p=0.02) and social aspects (p=0.04). The qi deficiency (?? qì xu) syndrome was closely associated with yin deficiency syndrome (?? yin xu). (p=0.03). Conclusion: Our study confirmed the concept of Qi-deficiency (?? qì xu) in TCM was associated with CRF as identified in cancer care in western medicine. The breast cancer patients with qi deficiency (?? qì xu) have poorer QoL. Treatment of CRF and improving QoL by supplying qi (? qì) may warrant further investigation. |
| PAST, PRESENT, AND FUTURE OF THE PULSE EXAMINATION (?? MÀI ZHEN) | Author : YUH-YING LIN WANG, SHENG-HUNG WANG, MING-YIE JAN, WEI-KUNG WANG | Abstract | Full Text | Abstract :The pulse examination (?? mài zhen) is a unique diagnostic approach of Traditional Chinese Medicine. The description of pulse examination in the history of Traditional Chinese Medicine is full of amazement and mythology. After researching in hemodynamics and investigating in clinical application for three decades, this article describes the development and the merits and demerits of pulse examination. The experiences of the ancients are tried to be illustrated with modern knowledge and language. As the theory of resonant blood circulation is discovered, Traditional Chinese Medicine could be on the shoulder of Newton and then lead the development of modern medicine. Hope the tool of pulse examination constructed according to eigen-vector with specific time domain and position can bring the running water for Traditional Chinese Medicine. Quantitative research could overcome the plight of analog logic qualitative research, and therefore bring new health revolution. |
| STACHYOSE: ONE OF THE ACTIVE FIBROBLAST-PROLIFERATING COMPONENTS IN THE ROOT OF REHMANNIAE RADIX (?? DÌ HUÁNG) | Author : PATRICK KWOK-KIN LAI, MING-HO TO, KIT-MAN LAU, CHEUK-LUN LIU, LING CHENG, KWOK-PUI FUNG, PING-CHUNG LEUNG, CLARA BIK-SAN LAU | Abstract | Full Text | Abstract : This study aimed to investigate and compare the fibroblast-proliferating activities of different Rehmanniae Radix (RR) samples and its chemical components using human normal fibroblast cells Hs27. Those active components were quantified in differently treated RR samples using UPLC so as to correlate activity with component content. Our results showed that dried RR aqueous extract exhibited the most potent fibroblast-proliferating activity. Stronger effect was observed when ethanol with heating was applied in the extraction process. Stachyose and verbascoside were demonstrated for their first time to exhibit significant stimulatory effects on fibroblast proliferation. However, the proliferating effect of dried RR extract did not correlate with the stachyose content, and verbascoside was not responsible for the fibroblast proliferative effect of RR since it was undetectable in all samples. In conclusion, stachyose only contributed in part to the activity of RR, suggesting that other active components might be present and yet to be found. |
| ANTI-ANXIETY ACTIVITY OF METHANOLIC EXTRACTS OF DIFFERENT PARTS OF ANGELICA ARCHANGELICA LINN | Author : DINESH KUMAR, ZULFIQAR ALI BHAT | Abstract | Full Text | Abstract :Angelica archangelica Linn.is a herb distributed in tropical and subtropical regions of the world. In Indian and Chinese system of medicine, it is used for nervous disorders and cerebral diseases. Previously the aqueous extract of the A. archangelica was evaluated for anxiolytic activity and was found to have significant potential for the same. The present study is aimed to evaluate the anxiolytic activity of methanol extract of root (MER), stem (MES), leaf (MEL), fruit (MEF) and whole plant (MEW) of Angelica archangelica Linn.All the extracts (MER, MES, MEL, MEF and MEW) were evaluated for anxiolytic effects using elevated plus maze test (EPM) model in rats. Methanol extracts of different parts of A.archangelica had increased number of entries and time spent in open arms while they decreased the number of entries and duration of time spent in closed arm of the EPM. In a similar fashion, the diazepam increased the percentage of time spent and percentage of arm entries in the open arms (*P 0.05, **P 0.01). Whole plant and the root had the maximum, leaf and fruits showed intermediate, while stem had the least anxiolytic activity (*P 0.05, **P 0.01) in EPM (Figure 1-5). The head dip count in DZ, SMR400, SML400, SMF400 and SMW400 in open arm are significantly shown in Table 1. The DZ, SMF400 and SMW did not show the fecal bolus while other groups were reduced the fecal bolus significantly (**P 0.01) as compared to control (Table 1). Whole plant and leaf showed the most, root and fruit the intermediate and stem the least anxiolytic activity (**P 0.01) in EPM. |
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